Mfsd2a and Spns2 are essential for sphingosine-1-phosphate transport in the formation and maintenance of the blood-brain barrier

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Science Advances  29 May 2020:
Vol. 6, no. 22, eaay8627
DOI: 10.1126/sciadv.aay8627

Article Information

vol. 6 no. 22

Online ISSN: 
  • Received for publication July 24, 2019
  • Accepted for publication March 18, 2020
  • .

Author Information

  1. Zhifu Wang1,2,*,
  2. Yongtao Zheng1,*,
  3. Fan Wang1,3,*,
  4. Junjie Zhong1,
  5. Tong Zhao1,
  6. Qiang Xie1,
  7. Tongming Zhu1,
  8. Fukai Ma1,
  9. Qisheng Tang1,
  10. Bin Zhou2, and
  11. Jianhong Zhu1,
  1. 1Department of Neurosurgery, Huashan Hospital, Institute of Brain Science, State Key laboratory of Medical Neurobiology, Shanghai Key Laboratory of Brain Function and Regeneration, Shanghai Medical College, Fudan University, No.12 Urumqi Mid Road, Shanghai 200040, China.
  2. 2State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), University of CAS, Shanghai, China.
  3. 3Department of Neurology, Peking University Third Hospital, Beijing, China.
  1. Corresponding author. Email: zhoubin{at} (B.Z.); jzhu{at} (J.Z.)
  • * These authors contributed equally to this work.


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