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Temporal pressure enhanced topical drug delivery through micropore formation

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Science Advances  29 May 2020:
Vol. 6, no. 22, eaaz6919
DOI: 10.1126/sciadv.aaz6919

Article Information

vol. 6 no. 22

PubMed: 
Online ISSN: 
History: 
  • Received for publication October 1, 2019
  • Accepted for publication March 6, 2020
  • .

Author Information

  1. Daniel Chin Shiuan Lio1,2,3,
  2. Rui Ning Chia3,
  3. Milton Sheng Yi Kwek2,3,
  4. Christian Wiraja1,
  5. Leigh Edward Madden3,4,
  6. Hao Chang1,
  7. S. Mohideen Abdul Khadir1,
  8. Xiaomeng Wang3,5,6,7,*,
  9. David L. Becker3,4,* and
  10. Chenjie Xu1,2,8,9,*
  1. 1School of Chemical and Biomedical Engineering, Nanyang Technological University, Nanyang Technological University, 62 Nanyang Drive, 637459, Singapore 637459, Singapore.
  2. 2NTU Institute for Health Technologies, Interdisciplinary Graduate School, Nanyang Technological University, 50 Nanyang Drive, Singapore 637553, Singapore.
  3. 3Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive Singapore 636921, Singapore.
  4. 4Skin Research Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 11 Mandalay Road, #17-01, Singapore 308232, Singapore.
  5. 5Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Proteos, 61 Biopolis Dr, Singapore 138673, Singapore.
  6. 6Singapore Eye Research Institute, The Academia, 20 College Road, Discovery Tower Level 6, Singapore 169856, Singapore.
  7. 7Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, UK.
  8. 8National Dental Centre of Singapore, 5 Second Hospital Ave, Singapore 168938, Singapore.
  9. 9Department of Biomedical Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong SAR, China.
  1. *Corresponding author. Email: wangxiaomeng{at}ntu.edu.sg (X.W.); david.becker{at}ntu.edu.sg (D.L.B.); chenjie.xu{at}cityu.edu.hk (C.X.)

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