Research ArticleIMMUNOLOGY

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

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Science Advances  27 May 2020:
Vol. 6, no. 22, eaba0468
DOI: 10.1126/sciadv.aba0468

Article Information

vol. 6 no. 22

PubMed: 
Online ISSN: 
History: 
  • Received for publication October 30, 2019
  • Accepted for publication March 19, 2020
  • .

Author Information

  1. Robyn L. Stanfield1,2,3,
  2. Zachary T. Berndsen1,2,3,
  3. Ruiqi Huang4,5,6,
  4. Devin Sok2,3,7,
  5. Gabrielle Warner4,5,6,
  6. Jonathan L. Torres1,2,3,
  7. Dennis R. Burton2,3,7,8,
  8. Andrew B. Ward1,2,3,*,
  9. Ian A. Wilson1,2,3,9,* and
  10. Vaughn V. Smider4,5,6,*
  1. 1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  2. 2IAVI, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  3. 3Scripps Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA.
  4. 4Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  5. 5Applied Biomedical Science Institute, San Diego, CA 92127, USA.
  6. 6Taurus Biosciences LLC, San Diego, CA 92127, USA.
  7. 7Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  8. 8Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02114, USA.
  9. 9Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  1. *Corresponding author. Email: andrew{at}scripps.edu (A.B.W.); wilson{at}scripps.edu (I.A.W.); vvsmider{at}scripps.edu (V.V.S.)

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