Research ArticleHEALTH AND MEDICINE

Nanoparticle-based thymulin gene therapy therapeutically reverses key pathology of experimental allergic asthma

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Science Advances  10 Jun 2020:
Vol. 6, no. 24, eaay7973
DOI: 10.1126/sciadv.aay7973

Article Information

vol. 6 no. 24

Online ISSN: 
History: 
  • Received for publication July 20, 2019
  • Accepted for publication April 15, 2020
  • .

Author Information

  1. Adriana L. da Silva1,2,
  2. Gisele P. de Oliveira1,
  3. Namho Kim3,4,
  4. Fernanda F. Cruz1,
  5. Jamil Z. Kitoko5,
  6. Natalia G. Blanco1,
  7. Sabrina V. Martini2,
  8. Justin Hanes3,4,6,
  9. Patricia R. M. Rocco1,
  10. Jung Soo Suk3,4,6,* and
  11. Marcelo M. Morales2,*
  1. 1Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  2. 2Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  3. 3Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  4. 4Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.
  5. 5Laboratory of Inflammation and Immunity, Paulo de Góes Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  6. 6Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  1. *Corresponding author. Email: jsuk{at}jhmi.edu (J.S.S.); mmorales{at}biof.ufrj.br (M.M.M.)

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