Research ArticleHEALTH AND MEDICINE
LiQD Cornea: Pro-regeneration collagen mimetics as patches and alternatives to corneal transplantation
- View ORCID ProfileChristopher D. McTiernan1,2,3,*,
- View ORCID ProfileFiona C. Simpson1,2,*,
- View ORCID ProfileMichel Haagdorens4,
- View ORCID ProfileChameen Samarawickrama5,6,
- Damien Hunter5,
- Oleksiy Buznyk6,
- Per Fagerholm6,
- View ORCID ProfileMonika K. Ljunggren6,
- View ORCID ProfilePhilip Lewis7,
- Isabel Pintelon8,
- David Olsen9,
- View ORCID ProfileElle Edin1,2,
- Marc Groleau1,
- View ORCID ProfileBruce D. Allan10,† and
- View ORCID ProfileMay Griffith1,2,†
- 1Centre de Recherche Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada.
- 2Department of Ophthalmology and Institute of Biomedical Engineering, Université de Montréal, Montréal, QC, Canada.
- 3Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, ON, Canada.
- 4Department of Ophthalmology, Visual Optics and Visual Rehabilitation, University of Antwerp, Antwerp, Belgium.
- 5Centre for Vision Research, The Westmead Institute for Medical Research, and Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
- 6Institute for Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
- 7School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK.
- 8Laboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.
- 9FibroGen Inc., San Francisco, CA, USA.
- 10NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
- ↵†Corresponding author. Email: may.griffith{at}umontreal.ca (M. Griffith); bruce.allan{at}ucl.ac.uk (B.D.A.)
↵* These authors contributed equally to this work.
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Science Advances 17 Jun 2020:
Vol. 6, no. 25, eaba2187
DOI: 10.1126/sciadv.aba2187
Vol. 6, no. 25, eaba2187
DOI: 10.1126/sciadv.aba2187
Christopher D. McTiernan
1Centre de Recherche Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada.
2Department of Ophthalmology and Institute of Biomedical Engineering, Université de Montréal, Montréal, QC, Canada.
3Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Fiona C. Simpson
1Centre de Recherche Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada.
2Department of Ophthalmology and Institute of Biomedical Engineering, Université de Montréal, Montréal, QC, Canada.
Michel Haagdorens
4Department of Ophthalmology, Visual Optics and Visual Rehabilitation, University of Antwerp, Antwerp, Belgium.
Chameen Samarawickrama
5Centre for Vision Research, The Westmead Institute for Medical Research, and Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
6Institute for Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Damien Hunter
5Centre for Vision Research, The Westmead Institute for Medical Research, and Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Oleksiy Buznyk
6Institute for Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Per Fagerholm
6Institute for Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Monika K. Ljunggren
6Institute for Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Philip Lewis
7School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK.
Isabel Pintelon
8Laboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.
David Olsen
9FibroGen Inc., San Francisco, CA, USA.
Elle Edin
1Centre de Recherche Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada.
2Department of Ophthalmology and Institute of Biomedical Engineering, Université de Montréal, Montréal, QC, Canada.
Marc Groleau
1Centre de Recherche Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada.
Bruce D. Allan
10NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
May Griffith
1Centre de Recherche Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada.
2Department of Ophthalmology and Institute of Biomedical Engineering, Université de Montréal, Montréal, QC, Canada.