Research ArticleCANCER

XAF1 as a modifier of p53 function and cancer susceptibility

See allHide authors and affiliations

Science Advances  24 Jun 2020:
Vol. 6, no. 26, eaba3231
DOI: 10.1126/sciadv.aba3231

Article Information

vol. 6 no. 26

Online ISSN: 
History: 
  • Received for publication November 26, 2019
  • Accepted for publication May 14, 2020
  • .

Author Information

  1. Emilia M. Pinto1,*,
  2. Bonald C. Figueiredo2,
  3. Wenan Chen3,
  4. Henrique C.R. Galvao4,
  5. Maria Nirvana Formiga5,
  6. Maria Candida B.V. Fragoso6,
  7. Patricia Ashton-Prolla7,
  8. Enilze M.S.F. Ribeiro8,
  9. Gabriela Felix9,
  10. Tatiana E.B. Costa10,
  11. Sharon A. Savage11,
  12. Meredith Yeager11,
  13. Edenir I. Palmero4,
  14. Sahlua Volc4,
  15. Hector Salvador12,
  16. Jose Luis Fuster-Soler13,
  17. Cinzia Lavarino12,
  18. Guillermo Chantada14,
  19. Dominique Vaur15,
  20. Vicente Odone-Filho16,
  21. Laurence Brugières17,
  22. Tobias Else18,
  23. Elena M. Stoffel18,
  24. Kara N. Maxwell19,
  25. Maria Isabel Achatz20,
  26. Luis Kowalski5,
  27. Kelvin C. de Andrade11,
  28. Alberto Pappo21,
  29. Eric Letouze22,
  30. Ana Claudia Latronico6,
  31. Berenice B. Mendonca6,
  32. Madson Q. Almeida6,
  33. Vania B. Brondani6,
  34. Camila M. Bittar7,
  35. Emerson W.S. Soares23,
  36. Carolina Mathias8,
  37. Cintia R.N. Ramos4,
  38. Moara Machado11,
  39. Weiyin Zhou11,
  40. Kristine Jones11,
  41. Aurelie Vogt11,
  42. Payal P. Klincha11,
  43. Karina M. Santiago5,
  44. Heloisa Komechen2,
  45. Mariana M. Paraizo2,
  46. Ivy Z.S. Parise2,
  47. Kayla V. Hamilton21,
  48. Jinling Wang1,
  49. Evadnie Rampersaud3,
  50. Michael R. Clay1,
  51. Andrew J. Murphy24,
  52. Enzo Lalli25,
  53. Kim E. Nichols21,
  54. Raul C. Ribeiro21,
  55. Carlos Rodriguez-Galindo14,
  56. Marta Korbonits26,
  57. Jinghui Zhang3,
  58. Mark G. Thomas27,
  59. Jon P. Connelly28,
  60. Shondra Pruett-Miller28,
  61. Yoan Diekmann27,
  62. Geoffrey Neale29,
  63. Gang Wu3 and
  64. Gerard P. Zambetti1,*
  1. 1Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN, USA.
  2. 2Instituto de Pesquisa Pelé Pequeno Principe, Curitiba, PR, Brazil.
  3. 3Center for Applied Bioinformatics, St. Jude Children’s Research Hospital, Memphis, TN, USA.
  4. 4Hospital de Cancer de Barretos, Barretos, SP, Brazil.
  5. 5A.C. Camargo Cancer Center, Sao Paulo, SP, Brazil.
  6. 6School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil.
  7. 7Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
  8. 8Federal University of Parana, Curitiba, PR, Brazil.
  9. 9Universidade Federal da Bahia, Salvador, BA, Brazil.
  10. 10Hospital Infantil Joana de Gusmao, Florianopolis, SC, Brazil.
  11. 11National Cancer Institute, Rockville, MD, USA.
  12. 12Pediatric Oncology Department, Sant Joan de Deu Hospital, Barcelona, Spain.
  13. 13Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain.
  14. 14Department of Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, TN, USA.
  15. 15Comprehensive Cancer Center François Baclesse, Caen, France.
  16. 16ITACI–Instituto de Tratamento do Câncer Infantil do Departamento de Pediatria da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, SP, Brazil.
  17. 17Institut Gustave Roussy, Villejuif, France.
  18. 18University of Michigan, Ann Arbor, MI, USA.
  19. 19Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, USA.
  20. 20Hospital Sírio-Libanes, Sao Paulo, SP, Brazil.
  21. 21Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN, USA.
  22. 22Centre de Recherche des Cordeliers, Paris, France.
  23. 23Hospital do Câncer de Cascavel–UOPECCAN, Cascavel, PR, Brazil.
  24. 24Department of Surgery, St. Jude Children’s Research Hospital, Memphis, TN, USA.
  25. 25Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
  26. 26Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  27. 27Research Department of Genetics, Evolution and Environment, University College London, London, UK.
  28. 28Center for Advanced Genome Engineering, St. Jude Children’s Research Hospital, Memphis, TN, USA.
  29. 29Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  1. *Corresponding author. Email: emilia.pinto{at}stjude.org (E.M.P.); gerard.zambetti{at}stjude.org (G.P.Z.)

Altmetric

Article usage

Article usage: June 2020 to July 2020

AbstractFullPdf
Jun 202035550501227
Jul 202068791194

Stay Connected to Science Advances

Navigate This Article