Research ArticleHEALTH AND MEDICINE
4D physiologically adaptable cardiac patch: A 4-month in vivo study for the treatment of myocardial infarction
- View ORCID ProfileHaitao Cui1,
- View ORCID ProfileChengyu Liu2,
- View ORCID ProfileTimothy Esworthy1,
- Yimin Huang2,
- Zu-xi Yu2,
- Xuan Zhou1,
- Hong San2,
- View ORCID ProfileSe-jun Lee1,
- Sung Yun Hann1,
- View ORCID ProfileManfred Boehm2,
- Muhammad Mohiuddin3,
- View ORCID ProfileJohn P. Fisher4 and
- View ORCID ProfileLijie Grace Zhang1,5,6,7,*
- 1Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA.
- 2National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
- 3Cardiac Xenotransplantation Program, Department of Surgery, University of Maryland, Baltimore, MD 21201, USA.
- 4Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA.
- 5Department of Electrical and Computer Engineering, The George Washington University, Washington, DC 20052, USA.
- 6Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA.
- 7Department of Medicine, The George Washington University, Washington, DC 20052, USA.
- ↵*Corresponding author. Email: lgzhang{at}gwu.edu
See allHide authors and affiliations
Science Advances 24 Jun 2020:
Vol. 6, no. 26, eabb5067
DOI: 10.1126/sciadv.abb5067
Vol. 6, no. 26, eabb5067
DOI: 10.1126/sciadv.abb5067
Haitao Cui
1Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA.
Chengyu Liu
2National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Timothy Esworthy
1Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA.
Yimin Huang
2National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Zu-xi Yu
2National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Xuan Zhou
1Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA.
Hong San
2National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Se-jun Lee
1Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA.
Sung Yun Hann
1Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA.
Manfred Boehm
2National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Muhammad Mohiuddin
3Cardiac Xenotransplantation Program, Department of Surgery, University of Maryland, Baltimore, MD 21201, USA.
John P. Fisher
4Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA.
Lijie Grace Zhang
1Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA.
5Department of Electrical and Computer Engineering, The George Washington University, Washington, DC 20052, USA.
6Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA.
7Department of Medicine, The George Washington University, Washington, DC 20052, USA.