Research ArticleHEALTH AND MEDICINE
Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines
- View ORCID ProfileAnjaneyulu Dirisala1,*,
- View ORCID ProfileSatoshi Uchida1,2,*,†,
- View ORCID ProfileKazuko Toh1,
- View ORCID ProfileJunjie Li1,
- View ORCID ProfileShigehito Osawa1,3,
- View ORCID ProfileTheofilus A. Tockary1,
- Xueying Liu1,
- View ORCID ProfileSaed Abbasi1,
- View ORCID ProfileKotaro Hayashi1,
- View ORCID ProfileYuki Mochida1,
- Shigeto Fukushima1,
- View ORCID ProfileHiroaki Kinoh1,
- View ORCID ProfileKensuke Osada4 and
- View ORCID ProfileKazunori Kataoka1,5,†
- 1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
- 2Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
- 3Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan.
- 4National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.
- 5Institute for Future Initiatives, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
- ↵†Corresponding author. Email: suchida{at}bmw.t.u-tokyo.ac.jp (S.U.); kataoka{at}ifi.u-tokyo.ac.jp (K.K.)
↵* These authors contributed equally to this work.
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Science Advances 26 Jun 2020:
Vol. 6, no. 26, eabb8133
DOI: 10.1126/sciadv.abb8133
Vol. 6, no. 26, eabb8133
DOI: 10.1126/sciadv.abb8133
Anjaneyulu Dirisala
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Satoshi Uchida
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
2Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Kazuko Toh
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Junjie Li
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Shigehito Osawa
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
3Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan.
Theofilus A. Tockary
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Xueying Liu
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Saed Abbasi
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Kotaro Hayashi
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Yuki Mochida
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Shigeto Fukushima
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Hiroaki Kinoh
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Kensuke Osada
4National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.
Kazunori Kataoka
1Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
5Institute for Future Initiatives, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
