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Emergence of SARS-CoV-2 through recombination and strong purifying selection

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Science Advances  01 Jul 2020:
Vol. 6, no. 27, eabb9153
DOI: 10.1126/sciadv.abb9153

Article Information

vol. 6 no. 27

PubMed: 
Online ISSN: 
History: 
  • Received for publication March 26, 2020
  • Accepted for publication May 19, 2020
  • .

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Author Information

  1. Xiaojun Li1,*,
  2. Elena E. Giorgi2,*,
  3. Manukumar Honnayakanahalli Marichannegowda1,
  4. Brian Foley2,
  5. Chuan Xiao3,
  6. Xiang-Peng Kong4,
  7. Yue Chen1,
  8. S. Gnanakaran2,
  9. Bette Korber2,5 and
  10. Feng Gao1,6,
  1. 1Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
  2. 2Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87544, USA.
  3. 3Department of Chemistry and Biochemistry, The University of Texas at El Paso, El Paso, TX 79968, USA.
  4. 4Department of Biochemistry and Molecular Pharmacology, Grossman School of Medicine, New York University, New York, NY 10016, USA.
  5. 5New Mexico Consortium, Los Alamos, NM 87545, USA.
  6. 6National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China.
  1. Corresponding author. Email: fgao{at}duke.edu
  • * These authors contributed equally to this work.

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