Research ArticleMICROBIOLOGY

Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiation

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Science Advances  15 Jan 2020:
Vol. 6, no. 3, eaay5781
DOI: 10.1126/sciadv.aay5781

Article Information

vol. 6 no. 3

Online ISSN: 
History: 
  • Received for publication July 1, 2019
  • Accepted for publication November 14, 2019
  • .

Author Information

  1. Zheren Zhang1,
  2. Chao Du1,
  3. Frédérique de Barsy1,
  4. Michael Liem1,
  5. Apostolos Liakopoulos1,
  6. Gilles P. van Wezel1,
  7. Young H. Choi2,3,
  8. Dennis Claessen1,* and
  9. Daniel E. Rozen1,*,
  1. 1Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.
  2. 2Natural Products Laboratory, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.
  3. 3College of Pharmacy, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, 02447 Seoul, Republic of Korea.
  1. Corresponding author. Email: d.e.rozen{at}biology.leidenuniv.nl
  • * Co-senior authors.

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