Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists

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Science Advances  15 Jan 2020:
Vol. 6, no. 3, eaay8230
DOI: 10.1126/sciadv.aay8230

Article Information

vol. 6 no. 3

Online ISSN: 
  • Received for publication July 21, 2019
  • Accepted for publication November 14, 2019
  • .

Author Information

  1. Jiaxuan Chen1,2,
  2. Carolyn A. Haller1,2,
  3. Finith E. Jernigan1,
  4. Steffi K. Koerner1,
  5. Daniel J. Wong1,
  6. Yiqiang Wang1,
  7. Jae Eun Cheong1,
  8. Revanth Kosaraju1,
  9. Julian Kwan3,
  10. Diane D. Park1,2,
  11. Beena Thomas4,
  12. Swati Bhasin4,
  13. Roberto C. De La Rosa1,5,
  14. Alykhan M. Premji1,
  15. Liying Liu1,
  16. Eden Park6,
  17. Alan C. Moss6,
  18. Andrew Emili3,
  19. Manoj Bhasin4,
  20. Lijun Sun1,*, and
  21. Elliot L. Chaikof1,2,*,
  1. 1Department of Surgery, Center for Drug Discovery and Translational Research, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
  2. 2Wyss Institute of Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, MA 02115, USA.
  3. 3Department of Biology and Biochemistry, Center for Network Systems Biology, Boston University School of Medicine, Boston, MA 02118, USA.
  4. 4BIDMC Genomics, Proteomics, Bioinformatics and Systems Biology Center, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  5. 5Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA.
  6. 6Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
  1. *Corresponding author. Email: echaikof{at} (E.L.C); lsun1{at} (L.S.)
  • These authors contributed equally to this work.


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