Research ArticleSTRUCTURAL BIOLOGY

Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM

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Science Advances  29 Jul 2020:
Vol. 6, no. 31, eabb2964
DOI: 10.1126/sciadv.abb2964

Article Information

vol. 6 no. 31

PubMed: 
Online ISSN: 
History: 
  • Received for publication February 13, 2020
  • Accepted for publication June 10, 2020
  • .

Author Information

  1. Kavita A. Iyer1,
  2. Yifan Hu1,
  3. Ashok R. Nayak1,
  4. Nagomi Kurebayashi2,
  5. Takashi Murayama2 and
  6. Montserrat Samsó1,*
  1. 1Department of Physiology and Biophysics, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
  2. 2Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  1. *Corresponding author. Email: montserrat.samso{at}vcuhealth.org

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