Research ArticleIMMUNOLOGY

Altered 3D chromatin structure permits inversional recombination at the IgH locus

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Science Advances  14 Aug 2020:
Vol. 6, no. 33, eaaz8850
DOI: 10.1126/sciadv.aaz8850

Article Information

vol. 6 no. 33

Online ISSN: 
History: 
  • Received for publication October 16, 2019
  • Accepted for publication July 1, 2020
  • .

Author Information

  1. Xiang Qiu1,*,
  2. Fei Ma1,*,
  3. Mingming Zhao1,
  4. Yaqiang Cao2,
  5. Lillian Shipp1,
  6. Angela Liu1,
  7. Arun Dutta1,
  8. Amit Singh1,
  9. Fatima Zohra Braikia1,
  10. Supriyo De3,
  11. William H. Wood III3,
  12. Kevin G. Becker3,
  13. Weiqiang Zhou4,
  14. Hongkai Ji4,
  15. Keji Zhao2,
  16. Michael L. Atchison5 and
  17. Ranjan Sen1,
  1. 1Laboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.
  2. 2Laboratory of Epigenome Biology, Systems Biology Center, National Heart Lung and Blood Institute, Bethesda, MD 20892, USA.
  3. 3Laboratory of Genetics and Genomics, National Institute on Aging, Baltimore, MD 21224, USA.
  4. 4Department of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
  5. 5Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  1. Corresponding author. Email: senranja{at}grc.nia.nih.gov
  • * These authors contributed equally to this work as co-first authors.

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