Research ArticleNEUROSCIENCE

Forward genetics identifies a novel sleep mutant with sleep state inertia and REM sleep deficits

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Science Advances  12 Aug 2020:
Vol. 6, no. 33, eabb3567
DOI: 10.1126/sciadv.abb3567

Article Information

vol. 6 no. 33

Online ISSN: 
  • Received for publication February 18, 2020
  • Accepted for publication June 29, 2020
  • .

Author Information

  1. Gareth T. Banks1,*,
  2. Mathilde C. C. Guillaumin2,*,,
  3. Ines Heise1,
  4. Petrina Lau1,
  5. Minghui Yin1,
  6. Nora Bourbia1,,
  7. Carlos Aguilar1,
  8. Michael R. Bowl1,
  9. Chris Esapa1,
  10. Laurence A. Brown2,
  11. Sibah Hasan2,
  12. Erica Tagliatti3,
  13. Elizabeth Nicholson3,
  14. Rasneer Sonia Bains4,
  15. Sara Wells4,
  16. Vladyslav V. Vyazovskiy5,2,
  17. Kirill Volynski3,
  18. Stuart N. Peirson2 and
  19. Patrick M. Nolan1,§
  1. 1Mammalian Genetics Unit, MRC Harwell Institute, Harwell Science and Innovation Campus, Oxfordshire, UK.
  2. 2Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
  3. 3UCL Queen Square Institute of Neurology, University College London, London, UK.
  4. 4Mary Lyon Centre, MRC Harwell Institute, Harwell Science and Innovation Campus, Oxfordshire, UK.
  5. 5Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
  1. §Corresponding author. Email: p.nolan{at}
  • * These authors contributed equally to this work.

  • Present address: Institute for Neuroscience, Department of Health Sciences and Technology (D-HEST), ETH Zürich, Switzerland.

  • Present address: Centre for Radiation, Public Health England, Harwell Science and Innovation Campus, Oxfordshire, UK.


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