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Research ArticleHEALTH AND MEDICINE
Anti-α4β7 monoclonal antibody–conjugated nanoparticles block integrin α4β7 on intravaginal T cells in rhesus macaques
- View ORCID ProfileSidi Yang1,
- View ORCID ProfileGeraldine Arrode-Bruses2,
- View ORCID ProfileInes Frank2,
- View ORCID ProfileBrooke Grasperge3,
- View ORCID ProfileJames Blanchard3,
- Agegnehu Gettie4,
- View ORCID ProfileElena Martinelli2,*,† and
- View ORCID ProfileEmmanuel A. Ho1,*,†
- 1School of Pharmacy, University of Waterloo, 10 Victoria St. S A, Kitchener, Ontario N2G 1C5, Canada.
- 2Center for Biomedical Research, Population Council, One Dag Hammarskjold Plaza, New York, NY 10017, USA.
- 3Tulane National Primate Research Center, Tulane University, 6823 St. Charles Ave., New Orleans, LA 70118, USA.
- 4Aaron Diamond AIDS Research Center, Rockefeller University, 455 1st Avenue #7, New York, NY 10016, USA.
- ↵*Corresponding author. Email: emmanuel.ho{at}uwaterloo.ca (E.A.H.); emartinelli{at}popcouncil.org (E.M.)
↵† These authors contributed equally to this work.
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Science Advances 21 Aug 2020:
Vol. 6, no. 34, eabb9853
DOI: 10.1126/sciadv.abb9853
Vol. 6, no. 34, eabb9853
DOI: 10.1126/sciadv.abb9853
Sidi Yang
1School of Pharmacy, University of Waterloo, 10 Victoria St. S A, Kitchener, Ontario N2G 1C5, Canada.
Geraldine Arrode-Bruses
2Center for Biomedical Research, Population Council, One Dag Hammarskjold Plaza, New York, NY 10017, USA.
Ines Frank
2Center for Biomedical Research, Population Council, One Dag Hammarskjold Plaza, New York, NY 10017, USA.
Brooke Grasperge
3Tulane National Primate Research Center, Tulane University, 6823 St. Charles Ave., New Orleans, LA 70118, USA.
James Blanchard
3Tulane National Primate Research Center, Tulane University, 6823 St. Charles Ave., New Orleans, LA 70118, USA.
Agegnehu Gettie
4Aaron Diamond AIDS Research Center, Rockefeller University, 455 1st Avenue #7, New York, NY 10016, USA.
Elena Martinelli
2Center for Biomedical Research, Population Council, One Dag Hammarskjold Plaza, New York, NY 10017, USA.
Emmanuel A. Ho
1School of Pharmacy, University of Waterloo, 10 Victoria St. S A, Kitchener, Ontario N2G 1C5, Canada.
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