Research ArticleGENETICS
Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons
- View ORCID ProfilePriscilla Turelli1,
- View ORCID ProfileChristopher Playfoot1,
- Dephine Grun1,*,
- View ORCID ProfileCharlène Raclot1,*,
- Julien Pontis1,
- Alexandre Coudray1,
- View ORCID ProfileChristian Thorball1,
- View ORCID ProfileJulien Duc1,
- View ORCID ProfileEugenia V. Pankevich1,2,
- View ORCID ProfileBart Deplancke1,
- View ORCID ProfileVolker Busskamp3,4 and
- View ORCID ProfileDidier Trono1,†
- 1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
- 2CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
- 3Center for Regenerative Therapies, Technische Universität Dresden, Dresden, Germany.
- 4Faculty of Medicine, Department of Ophthalmology, University of Bonn, Bonn, Germany.
- ↵†Corresponding author. Email: didier.trono{at}epfl.ch
↵* These authors contributed equally to this work.
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Science Advances 28 Aug 2020:
Vol. 6, no. 35, eaba3200
DOI: 10.1126/sciadv.aba3200
Vol. 6, no. 35, eaba3200
DOI: 10.1126/sciadv.aba3200
Priscilla Turelli
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Christopher Playfoot
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Dephine Grun
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Charlène Raclot
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Julien Pontis
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Alexandre Coudray
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Christian Thorball
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Julien Duc
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Eugenia V. Pankevich
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
2CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Bart Deplancke
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Volker Busskamp
3Center for Regenerative Therapies, Technische Universität Dresden, Dresden, Germany.
4Faculty of Medicine, Department of Ophthalmology, University of Bonn, Bonn, Germany.
Didier Trono
1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.