Research ArticleMOLECULAR BIOLOGY

Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier

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Science Advances  28 Aug 2020:
Vol. 6, no. 35, eaba7457
DOI: 10.1126/sciadv.aba7457

Article Information

vol. 6 no. 35

Online ISSN: 
History: 
  • Received for publication December 31, 2019
  • Accepted for publication July 15, 2020
  • .

Author Information

  1. Zhongxiao Wang1,
  2. Chi-Hsiu Liu1,
  3. Shuo Huang1,
  4. Zhongjie Fu1,
  5. Yohei Tomita1,
  6. William R. Britton1,
  7. Steve S. Cho1,
  8. Chuck T. Chen2,
  9. Ye Sun1,
  10. Jian-xing Ma3,
  11. Xi He4 and
  12. Jing Chen1,*
  1. 1Department of Ophthalmology, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  2. 2Section on Nutritional Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 3N-01, North Bethesda, MD 20852, USA.
  3. 3Department of Physiology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  4. 4The F.M. Kirby Neurobiology Center, Boston Children’s Hospital, Department of Neurology, Harvard Medical School, Boston, MA 02115, USA.
  1. *Corresponding author. Email: jing.chen{at}childrens.harvard.edu

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