Research ArticleIMMUNOLOGY

Global and local envelope protein dynamics of hepatitis C virus determine broad antibody sensitivity

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Science Advances  26 Aug 2020:
Vol. 6, no. 35, eabb5938
DOI: 10.1126/sciadv.abb5938

Article Information

vol. 6 no. 35

Online ISSN: 
History: 
  • Received for publication March 5, 2020
  • Accepted for publication July 13, 2020
  • .

Author Information

  1. Elias H. Augestad1,
  2. Matteo Castelli2,
  3. Nicola Clementi2,
  4. Luisa J. Ströh3,
  5. Thomas Krey3,4,5,6,7,
  6. Roberto Burioni2,
  7. Nicasio Mancini2,
  8. Jens Bukh1 and
  9. Jannick Prentoe1,*
  1. 1Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
  2. 2Laboratory of Microbiology and Virology, Università “Vita-Salute” San Raffaele, Milano, 20132, Italy.
  3. 3Institute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany.
  4. 4German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Germany.
  5. 5Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Luebeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
  6. 6Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
  7. 7Centre for Structural Systems Biology (CSSB), Notkestraße 85, 22607 Hamburg, Germany.
  1. *Corresponding author. Email: jprentoe{at}sund.ku.dk

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