Contents
September 2020
Vol 6, Issue 37
Vol 6, Issue 37
Contents
Research Articles
- Immobilized 13C-labeled polyether chain ends confined to the crystallite surface detected by advanced NMR
Polymer chain ends mostly confined to crystallite surfaces have been detected by versatile isotope labeling and advanced NMR.
- Molecular characterization of ebselen binding activity to SARS-CoV-2 main protease
Atomistic molecular dynamics simulation characterizes ebselen binding activity to SARS-CoV-2 main protease.
- LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium
Early-life intestinal epithelial development is controlled by the epigenetic modifier LSD1.
- Generating multifunctional acoustic tweezers in Petri dishes for contactless, precise manipulation of bioparticles
Acoustic tweezers enable contactless, dynamic, precise, and multifunctional manipulation of bioparticles in Petri dishes.
- Mid-infrared polarization-controlled broadband achromatic metadevice
This study presents a platform to realize polarization-controlled broadband achromatic metadevice in mid-wavelength infrared.
- The optoretinogram reveals the primary steps of phototransduction in the living human eye
Human cone photoreceptors undergo rapid nanometer-scale mechanical deformations during the first step of phototransduction.
- Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing
Integrative single-cell analysis de-constructs the heterogeneity of human reprogramming and uncovers its stage-specific GRNs.
- 3D bioprinting dual-factor releasing and gradient-structured constructs ready to implant for anisotropic cartilage regeneration
3D bioprinting helps to reconstruct your broken knee.
- Gadofullerene inhibits the degradation of apolipoprotein B100 and boosts triglyceride transport for reversing hepatic steatosis
Fullerene nanomaterials protect the liver from lipid accumulation by promoting the transport of lipids out of liver.
- Dimorphism in cryptophytes—The case of Teleaulax amphioxeia/Plagioselmis prolonga and its ecological implications
Microscopic algae have sex too, and it is an important aspect of their ecological success.
- Revealing hidden medium-range order in amorphous materials using topological data analysis
Hidden medium-range structural features of disordered materials can be extracted through persistent homology analyses.
- Paleozoic ammonoid ecomorphometrics test ecospace availability as a driver of morphological diversification
Paleozoic ammonoid ecomorphometrics show no support for early bursts at origination or during mass extinction recoveries.
- Hypothalamic circuitry underlying stress-induced insomnia and peripheral immunosuppression
Activation of a neural circuit that triggers an acute stress response increases wakefulness and changes the immune landscape.
- Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents
Extracellular matrix stiffness controls DNA damage response.
- Self-luminescent photodynamic therapy using breast cancer targeted proteins
Bioluminescence-induced proteinaceous photodynamic therapy enables cancer treatment by self-luminescent ROS generation.
- Cost-effective priorities for the expansion of global terrestrial protected areas: Setting post-2020 global and national targets
Cost-effective zones for the expansion of global terrestrial protected areas are identified.
- High-sensitivity nanoscale chemical imaging with hard x-ray nano-XANES
Hard x-ray nano-XANES enables high-sensitivity chemical state mapping at the nanoscale and multimodal imaging capability.
- Deconstructing laws of accessibility and facility distribution in cities
Interplay between facilities and population in cities is studied and a universal function is found to model optimal accessibility.
- Quantum key distribution with correlated sources
A security framework enables practical quantum key distribution realizations even with correlated and generally flawed sources.
- Temperature dependence of elastic and plastic deformation behavior of a refractory high-entropy alloy
The present work discovers the unique deformation behavior of a refractory high-entropy alloy at elevated temperatures.
- Microengineered 3D pulmonary interstitial mimetics highlight a critical role for matrix degradation in myofibroblast differentiation
Tissue-engineered fibrosis model highlights distinct cell responses to matrix stiffness and drug treatment in 2D versus 3D.
- Efficient high-throughput SARS-CoV-2 testing to detect asymptomatic carriers
Single-stage group testing uses compressed sensing for efficient high-throughput SARS-CoV-2 testing.
- B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis
B cells have a previously unrecognized helper function in triggering pathogenic differentiation of inflammatory TH subsets.
- Real-time shaping of entangled photons by classical control and feedback
Shaping the classical laser that stimulates generation of entangled photons allows optimization of their quantum correlations.
- Deciphering the effect of traps on electronic charge transport properties of methylammonium lead tribromide perovskite
Unique detrapping activity in perovskites prevents free carrier recombination leading to more efficient optoelectronic devices.
- Propagation and attenuation of mechanical signals in ultrasoft 2D solids
We analyze wave propagation and attenuation in extremely soft, strongly overdamped solids both experimentally and theoretically.
- Tailoring of the axon initial segment shapes the conversion of synaptic inputs into spiking output in OFF-α T retinal ganglion cells
Intrinsic properties of retinal ganglion cells are tailored to their synaptic inputs to ensure reliable spiking output.
- An enormous sulfur isotope excursion indicates marine anoxia during the end-Triassic mass extinction
Low ocean sulfate levels at the end-Triassic mass extinction linked to rapid development of marine anoxia.
- Let-7 derived from endometrial extracellular vesicles is an important inducer of embryonic diapause in mice
Let-7 in endometrial epithelial cell–derived extracellular vesicles induces embryonic diapause.
- Hedgehog signaling controls segmentation dynamics and diversity via msx1 in a spider embryo
A genome-wide study of Hedgehog signaling reveals a previously unknown mechanism of segmentation in a chelicerate arthropod.
- Political storms: Emergent partisan skepticism of hurricane risks
Following conservative media skepticism of hurricane warnings in 2017, a partisan wedge in evacuation behavior rapidly emerged.
- Intrinsic reconstruction of ice-I surfaces
Atomic force microscopy showed that the reconstruction of ice-I surfaces occurs with a short-range (2 × 2) H-atom order.
- Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling
GPCR–β-arrestin interaction and signaling are differentially regulated by distinct phosphorylation sites on the receptor.
- Aberration-corrected STEM imaging of 2D materials: Artifacts and practical applications of threefold astigmatism
Phase off: false phase emerges in scanning transmission electron microscopy (STEM) imaging of 2D Materials.
- Highly energy-tunable quantum light from moiré-trapped excitons
Photon antibunching, a hallmark of quantum light, is observed from moiré-trapped interlayer excitons in a 2D heterobilayer.
- Increased vaccine tolerability and protection via NF-κB modulation
Inflammation can be decoupled from the antigen-presenting actions of adjuvants using an immune potentiator that modulates NF-κB.
- Real-time nanodiamond thermometry probing in vivo thermogenic responses
Nanoparticle quantum temperature sensors detect subcellular heat generation in a multicellular model organism.
- PhenomeXcan: Mapping the genome to the phenome through the transcriptome
PhenomeXcan is a gene-based resource of gene-trait associations, providing biological contexts for translational research.
- Tissue-specific genetic features inform prediction of drug side effects in clinical trials
Tissue-specific genetic features in multiple tissues can inform prediction of drug side effects in clinical trials.
Reviews
- Directional liquid dynamics of interfaces with superwettability
We review advances in the field of directional liquid dynamics on natural and artificial surfaces with superwettability.
- The distribution of biodiversity richness in the tropics
Latin America has more than twice as many vascular plant species as Africa south of the Sahara plus Madagascar, in a smaller area.
Editorial
About The Cover
ONLINE COVER In nature, plants and animals have adapted to take advantage of the physical properties of water, controlling its fluid dynamics so to aid in their survival. For example, pitcher plants in the tropics form a lubricating water layer from condensation that causes insects to slip into their trap, while shorebirds perform a tweezer-like motion with their beaks to drive the movement of water into their mouths. In this review, Dai et al. describe how these natural phenomena have inspired artificial superwetting materials, which have been manipulated to enhance their ability to interact with water. Materials that rely on these surface-water interactions have recently been tested for applications in fog collection, 3D printing, energy devices, liquid-liquid separation, soft machines, and sensors. The researchers suggest that the efficiency of directional liquid dynamics could be further improved in the future by combining external stimulation with artificial structures modeled after those found in nature. [CREDIT: SCIENCE PHOTO LIBRARY/SCIENCE SOURCE]
