Research ArticleIMMUNOLOGY

Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation

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Science Advances  23 Sep 2020:
Vol. 6, no. 39, eabc5447
DOI: 10.1126/sciadv.abc5447

Article Information

vol. 6 no. 39

PubMed: 
Online ISSN: 
History: 
  • Received for publication April 30, 2020
  • Accepted for publication August 11, 2020
  • .

Author Information

  1. Junke Long1,2,*,
  2. Chenxuan Yang3,4,*,
  3. Yawen Zheng2,5,
  4. Patricia Loughran6,7,
  5. Fu Guang2,8,
  6. Yiming Li9,10,
  7. Hong Liao6,
  8. Melanie J. Scott6,
  9. Daolin Tang11,
  10. Timothy R. Billiar6,, and
  11. Meihong Deng6,,
  1. 1Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
  2. 2Department of Surgery current visiting research scholar, University of Pittsburgh, Pittsburgh, PA, USA.
  3. 3Tsinghua University School of Medicine, Beijing, China.
  4. 4Department of Surgery former visiting research scholar; 10/24/2016 to 7/27/2018, University of Pittsburgh, Pittsburgh, PA, USA.
  5. 5Department of Urological Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
  6. 6Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
  7. 7Center for Biological Imaging, University of Pittsburgh, Pittsburgh, PA, USA.
  8. 8Department of General Surgery, The Third Xiangya Hospital of Central South University, Changsha 410011, China.
  9. 9Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei, China.
  10. 10Department of Surgery former visiting research scholar; 9/1/2018 to 1/31/2020, University of Pittsburgh, Pittsburgh, PA, USA.
  11. 11Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USA.
  1. Corresponding author. Email: billiartr{at}upmc.edu (T.R.B.); dengm{at}upmc.edu (M.D.)
  • * These authors contributed equally to this work.

  • These authors contributed equally to this work as co-senior authors.

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