Contents
January 2020
Vol 6, Issue 4
Vol 6, Issue 4
Contents
Research Articles
- Deficient histone H3 propionylation by BRPF1-KAT6 complexes in neurodevelopmental disorders and cancer
Two lysine acyltransferases govern histone H3 propionylation at lysine 23 in normal and pathological conditions.
- Can polarity-inverted membranes self-assemble on Titan?
Can polarity-inverted membranes self-assemble on Titan, and what does it mean for astrobiology under cryogenic conditions?
- Multidimensional entanglement transport through single-mode fiber
This work suggests a new approach to multidimensional entanglement transport through conventional single-mode fiber.
- On the design of precision nanomedicines
We propose nanomedicines able to target cells phenotypically that bind when a precise combination of receptors is expressed.
- Community detection in networks without observing edges
We present a principled approach for detecting communities in networks that uses only observations of interdependent node signals.
- Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism
Extremely simple poly(vinyl alcohol) enhances therapeutic potential of p-boronophenylalanine by modulating its metabolism.
- Multi-isotope evidence for the emergence of cultural alterity in Late Neolithic Europe
Multi-isotope analyses suggest cultural differentiation as the primary reason for Late Neolithic variability in burial location.
- Animal simulations facilitate smart drug design through prediction of nanomaterial transport to individual tissue cells
A state-of-the-art in vitro to in silico animal body simulation successfully predicts biodistribution with cellular resolution.
- Environmental and genetic determinants of plasmid mobility in pathogenic Escherichia coli
Integrating genomics with growth-based phenotyping reveals divergent roles of antibiotics and incompatibility in plasmid mobility.
- Structural and spectral dynamics of single-crystalline Ruddlesden-Popper phase halide perovskite blue light-emitting diodes
Heat-induced perovskite LED device degradation is elucidated via insightful in situ structure and spectroscopy characterizations.
- Atmospheric CO2 levels from 2.7 billion years ago inferred from micrometeorite oxidation
Iron-rich micrometeorites from a 2.7 billion-year-old limestone could constrain atmospheric CO2 levels on the early Earth.
- Seismic evidence for megathrust fault-valve behavior during episodic tremor and slip
Recurring slow slip and tremor events at subduction zones are accompanied by fluctuations in pore-fluid pressure.
- Direct observation of glucose fingerprint using in vivo Raman spectroscopy
Noninvasive optical sensor can measure blood glucose levels based on the glucose Raman signal from in vivo skin.
- Compression-induced dedifferentiation of adipocytes promotes tumor progression
Physical compression–induced dedifferentiation of adipocytes promotes tumor progression.
- Isothermal digital detection of microRNAs using background-free molecular circuit
We report the isothermal digital detection of microRNAs using DNA circuits encoding a background-free amplification mechanism.
- Imperceptible magnetic sensor matrix system integrated with organic driver and amplifier circuits
Imperceptible magnetic sensor matrix system realizes real-time mapping of 2D magnetic field distribution.
- Small-scale universality in the spectral structure of transitional pipe flows
The flashes of transitional pipe flows are turbulent, in the sense of Kolmogorov.
- A highly scalable dielectric metamaterial with superior capacitor performance over a broad temperature
Interface effects in a new class of nanocomposites generate superior energy storage performance over broad temperatures.
- Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer’s disease
Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer’s disease.
- Single-cell morphology encodes metastatic potential
Cancer cell population exhibits great cellular heterogeneity, and single-cell morphology encodes metastatic potential.
- Weak-field induced nonmagnetic state in a Co-based honeycomb
The order associated with non-Kitaev interactions in a 3d layered honeycomb magnet is suppressed by a low magnetic field.
- Different motilities of microtubules driven by kinesin-1 and kinesin-14 motors patterned on nanopillars
Nanopatterning of motors reveals that the number and spacing of kinesin-14, and not of kinesin-1, dictate microtubule velocity.
- Molecular identification of fungi microfossils in a Neoproterozoic shale rock
We report the discovery of 715 to ca. 810 million–year–old fungal fossils through molecular characterization of vestigial chitin.
- Cargo capture and transport by colloidal swarms
Multiagent stochastic control enables self-propelled colloidal swarms to perform cooperative tasks as micromachines.
- Bioinspired structural color patch with anisotropic surface adhesion
Multifunctional bioinspired structural color patch with anisotropic surface adhesion was designed for biomedical applications.
- Dense hydroxyl polyethylene glycol dendrimer targets activated glia in multiple CNS disorders
PEGOL-60, a ligand-free high hydroxyl surface density dendrimer, targets neuroinflammation from systemic administration.
- The global-scale distributions of soil protists and their contributions to belowground systems
We studied the dominant protists found in soils across the globe and their contributions to belowground food webs.
- Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection
We found a new type of white blood cell induced by bacterial infection that has lethal effects on host survival.
- Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis
Monoubiquitination of p120-catenin controls adherens junction dissociation in TGFβ-induced EMT.
- Large-scale synthesis of crystalline g-C3N4 nanosheets and high-temperature H2 sieving from assembled films
Atom-thick poly(triazine imide) nanosheets hosting ordered triangular nanopores led to high-performance hydrogen sieving.
About The Cover
ONLINE COVER Scientists have recently made progress in developing flexible, imperceptible electronic sensors for artificial electronic skins (e-skins), which must be able to perceive physical interactions between their robot or human wearer and the objects they touch. However, few studies have explored advanced, flexible magnetic systems that combine individual magnetic sensors with other electronic devices. Kondo et al. demonstrated the first fully functional imperceptible magnetic sensor matrix system based on flexible organic thin-film transistor technology, the most seamless, complex, and high-functioning system of its kind to date. The system integrates a bootstrap matrix-driver circuit, which consumes three orders of magnitude less static power than traditional organic drivers, as well as a high-gain signal amplifier, switching transistors, and current-source amplifiers. The researchers demonstrated that the system is able to accurately map magnetic fields in two dimensions and can operate at low supply voltages (below 4 volts) and high frequencies (about 100 hertz). This technological development could help introduce a new generation of flexible electronics, which may be used in e-skins, soft robotics, and biomedicine. [CREDIT: TSUYOSHI SEKITANI, ISIR, OSAKA UNIVERSITY]
