Research ArticleIMMUNOLOGY

Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4+Foxp3+ regulatory T cells

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Science Advances  30 Sep 2020:
Vol. 6, no. 40, eaba6584
DOI: 10.1126/sciadv.aba6584

Article Information

vol. 6 no. 40

Online ISSN: 
  • Received for publication December 20, 2019
  • Accepted for publication August 10, 2020
  • .

Author Information

  1. Tianzhen He1,
  2. De Yang2,
  3. Xiao-Qing Li2,3,
  4. Mengmeng Jiang1,
  5. Md Sahidul Islam1,
  6. Shaokui Chen1,
  7. Yibo Chen1,
  8. Yang Yang1,
  9. Chon-Kit Chou1,
  10. Anna L. Trivett2,
  11. Joost J. Oppenheim2,* and
  12. Xin Chen1,*
  1. 1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
  2. 2Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, NIH, Frederick, MD, USA.
  3. 3Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
  1. *Corresponding author. Email: xchen{at} (X.C.); oppenhej{at} (J.J.O.)


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