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Research ArticleIMMUNOLOGY
Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4+Foxp3+ regulatory T cells
- View ORCID ProfileTianzhen He1,
- View ORCID ProfileDe Yang2,
- View ORCID ProfileXiao-Qing Li2,3,
- View ORCID ProfileMengmeng Jiang1,
- Md Sahidul Islam1,
- Shaokui Chen1,
- Yibo Chen1,
- Yang Yang1,
- Chon-Kit Chou1,
- View ORCID ProfileAnna L. Trivett2,
- View ORCID ProfileJoost J. Oppenheim2,* and
- View ORCID ProfileXin Chen1,*
- 1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
- 2Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, NIH, Frederick, MD, USA.
- 3Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
- ↵*Corresponding author. Email: xchen{at}umac.mo (X.C.); oppenhej{at}mail.nih.gov (J.J.O.)
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Science Advances 30 Sep 2020:
Vol. 6, no. 40, eaba6584
DOI: 10.1126/sciadv.aba6584
Vol. 6, no. 40, eaba6584
DOI: 10.1126/sciadv.aba6584
Tianzhen He
1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
De Yang
2Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, NIH, Frederick, MD, USA.
Xiao-Qing Li
2Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, NIH, Frederick, MD, USA.
3Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
Mengmeng Jiang
1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Md Sahidul Islam
1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Shaokui Chen
1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Yibo Chen
1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Yang Yang
1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Chon-Kit Chou
1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
Anna L. Trivett
2Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, NIH, Frederick, MD, USA.
Joost J. Oppenheim
2Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, NIH, Frederick, MD, USA.
Xin Chen
1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR 999078, China.
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