Research ArticleCELL BIOLOGY

The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase

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Science Advances  02 Oct 2020:
Vol. 6, no. 40, eabb7854
DOI: 10.1126/sciadv.abb7854

Article Information

vol. 6 no. 40

PubMed: 
Online ISSN: 
History: 
  • Received for publication March 18, 2020
  • Accepted for publication August 7, 2020
  • .

Author Information

  1. Riyad N. H. Seervai1,2,3,*,
  2. Rahul K. Jangid2,
  3. Menuka Karki2,
  4. Durga Nand Tripathi1,2,
  5. Sung Yun Jung4,
  6. Sarah E. Kearns5,6,7,
  7. Kristen J. Verhey5,
  8. Michael A. Cianfrocco6,7,
  9. Bryan A. Millis8,9,
  10. Matthew J. Tyska8,
  11. Frank M. Mason10,
  12. W. Kimryn Rathmell10,
  13. In Young Park2,*,
  14. Ruhee Dere2,* and
  15. Cheryl Lyn Walker1,2,11,12,13,*,
  1. 1Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  2. 2Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA.
  3. 3Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, USA.
  4. 4Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  5. 5Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  6. 6Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  7. 7Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  8. 8Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
  9. 9Vanderbilt Biophotonics Center, Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37240, USA.
  10. 10Vanderbilt-Ingram Cancer Center, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  11. 11Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
  12. 12Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  13. 13Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  1. *Corresponding author. Email: riyad.seervai{at}bcm.edu (R.N.H.S.); cheryl.walker{at}bcm.edu (C.L.W.); ipark{at}bcm.edu (I.Y.P.); dere{at}bcm.edu (R.D.)
  • Lead contact.

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