Research ArticleSTRUCTURAL BIOLOGY

Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1

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Science Advances  30 Sep 2020:
Vol. 6, no. 40, eabd1882
DOI: 10.1126/sciadv.abd1882

Article Information

vol. 6 no. 40

PubMed: 
Online ISSN: 
History: 
  • Received for publication June 5, 2020
  • Accepted for publication August 4, 2020
  • .

Author Information

  1. Olivier Soubias1,*,
  2. Shashank Pant2,*,
  3. Frank Heinrich3,4,*,
  4. Yue Zhang1,
  5. Neeladri Sekhar Roy5,
  6. Jess Li1,
  7. Xiaoying Jian5,
  8. Marielle E. Yohe6,
  9. Paul A. Randazzo5,
  10. Mathias Lösche3,4,7,,
  11. Emad Tajkhorshid2, and
  12. R. Andrew Byrd1,
  1. 1Structural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702-1201, USA.
  2. 2NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  3. 3Department of Physics, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
  4. 4NIST Center for Neutron Research, Gaithersburg, MD 20878, USA.
  5. 5Laboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  6. 6Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  7. 7Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
  1. Corresponding author. Email: loesche{at}andrew.cmu.edu (M.L.); emad{at}life.illinois.edu (E.T.); byrdra{at}mail.nih.gov (R.A.B.)
  • * These authors contributed equally to this work.

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