Research ArticleHEALTH AND MEDICINE
Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells
- View ORCID ProfileRohiverth Guarecuco1,
- Robert T. Williams1,
- Lou Baudrier1,
- Konnor La1,2,3,
- View ORCID ProfileMaria C. Passarelli4,
- View ORCID ProfileNaz Ekizoglu1,5,
- View ORCID ProfileMert Mestanoglu1,5,
- Hanan Alwaseem6,
- View ORCID ProfileBety Rostandy6,
- Justine Fidelin6,
- View ORCID ProfileJavier Garcia-Bermudez1,
- View ORCID ProfileHenrik Molina6 and
- View ORCID ProfileKıvanç Birsoy1,*
- 1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
- 2Tri-Institutional Program in Computational Biology and Medicine, New York, NY 10065, USA.
- 3Department of Computational Biology, Cornell University, Ithaca, NY 14853, USA.
- 4Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY 10065, USA.
- 5Bahçeşehir University School of Medicine, Istanbul, Turkey.
- 6Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
- ↵*Corresponding author. Email: kbirsoy{at}rockefeller.edu
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Science Advances 09 Oct 2020:
Vol. 6, no. 41, eabc7120
DOI: 10.1126/sciadv.abc7120
Vol. 6, no. 41, eabc7120
DOI: 10.1126/sciadv.abc7120
Rohiverth Guarecuco
1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
Robert T. Williams
1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
Lou Baudrier
1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
Konnor La
1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
2Tri-Institutional Program in Computational Biology and Medicine, New York, NY 10065, USA.
3Department of Computational Biology, Cornell University, Ithaca, NY 14853, USA.
Maria C. Passarelli
4Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY 10065, USA.
Naz Ekizoglu
1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
5Bahçeşehir University School of Medicine, Istanbul, Turkey.
Mert Mestanoglu
1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
5Bahçeşehir University School of Medicine, Istanbul, Turkey.
Hanan Alwaseem
6Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
Bety Rostandy
6Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
Justine Fidelin
6Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
Javier Garcia-Bermudez
1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
Henrik Molina
6Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
Kıvanç Birsoy
1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY 10065, USA.
