October 2020
Vol 6, Issue 42

About The Cover

Cover image expansion

ONLINE COVER Microscopes that use mid-infrared (mid-IR) light are powerful, promising tools for biomedical and industrial applications. However, mid-IR light is not as commonly used in laboratories as visible and near-infrared light since technologies designed to detect mid-IR light are technically demanding, expensive, weighed down by import restrictions, and inferior in performance. To overcome these challenges, Kviatkovsky et al. demonstrated a technique that involves performing non-linear interferometry with entangled light, requiring only an off-the-shelf complementary metal oxide semiconductor (CMOS) camera. The technique enables mid-IR microscopy without a light source or detection in the mid-IR. The researchers successfully used this workaround to image tissue from a mouse heart and demonstrated its imaging abilities over a broad 3.4 to 4.3 μm wavelength range. The results suggest this quiet, fast, and cost-effective imaging technique may be superior to state-of-the-art technologies and could be used for quantum imaging in the life sciences. [CREDIT: KVIATKOVSKY ET AL./SCIENCE ADVANCES]