Research ArticleMOLECULAR BIOLOGY

cGAS suppresses genomic instability as a decelerator of replication forks

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Science Advances  14 Oct 2020:
Vol. 6, no. 42, eabb8941
DOI: 10.1126/sciadv.abb8941

Article Information

vol. 6 no. 42

PubMed: 
Online ISSN: 
History: 
  • Received for publication March 25, 2020
  • Accepted for publication August 28, 2020
  • .

Author Information

  1. Hao Chen1,2,
  2. Hao Chen3,
  3. Jiamin Zhang1,
  4. Yumin Wang1,2,
  5. Antoine Simoneau1,4,
  6. Hui Yang5,6,
  7. Arthur S. Levine3,
  8. Lee Zou1,4,
  9. Zhijian Chen5,6 and
  10. Li Lan1,2,*
  1. 1Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02129, USA.
  2. 2Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115, USA.
  3. 3UPMC Hillman Cancer Center, 5117 Centre Avenue, Pittsburgh, PA 15213, USA.
  4. 4Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115, USA.
  5. 5Department of Molecular Biology, Center for Inflammation Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
  6. 6Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
  1. *Corresponding author. Email: llan1{at}mgh.harvard.edu

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