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Therapeutics potentiating microglial p21-Nrf2 axis can rescue neurodegeneration caused by neuroinflammation

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Science Advances  13 Nov 2020:
Vol. 6, no. 46, eabc1428
DOI: 10.1126/sciadv.abc1428

Article Information

vol. 6 no. 46

Online ISSN: 
  • Received for publication April 8, 2020
  • Accepted for publication October 1, 2020
  • .

Author Information

  1. A. Nakano-Kobayashi1,*,
  2. A. Fukumoto2,
  3. A. Morizane2,
  4. D. T. Nguyen3,
  5. T. M. Le3,
  6. K. Hashida3,
  7. T. Hosoya4,
  8. R. Takahashi5,
  9. J. Takahashi2,
  10. O. Hori3 and
  11. M. Hagiwara1,*
  1. 1Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  2. 2Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
  3. 3Department of Neuroanatomy, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan.
  4. 4Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan.
  5. 5Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  1. *Corresponding author. Email: kobayashi.akiko.5e{at} (A.N.-K.); hagiwara.masatoshi.8c{at} (M.H)


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