Research ArticleNEUROSCIENCE

Determinants of seeding and spreading of α-synuclein pathology in the brain

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Science Advances  11 Nov 2020:
Vol. 6, no. 46, eabc2487
DOI: 10.1126/sciadv.abc2487

Article Information

vol. 6 no. 46

PubMed: 
Online ISSN: 
History: 
  • Received for publication April 16, 2020
  • Accepted for publication September 22, 2020
  • .

Author Information

  1. Martin T. Henrich1,2,*,
  2. Fanni F. Geibl2,*,
  3. Harini Lakshminarasimhan1,
  4. Anna Stegmann2,
  5. Benoit I. Giasson3,
  6. Xiaobo Mao4,5,
  7. Valina L. Dawson4,5,6,7,
  8. Ted M. Dawson4,5,6,8,
  9. Wolfgang H. Oertel2, and
  10. D. James Surmeier1,,
  1. 1Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  2. 2Department of Neurology, Philipps University Marburg, Marburg 35043, Germany.
  3. 3Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA.
  4. 4Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  5. 5Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  6. 6Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  7. 7Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  8. 8Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  1. Corresponding author. Email: j-surmeier{at}northwestern.edu
  • * These authors contributed equally to this work.

  • These authors contributed to this work as co-senior authors.

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