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Targeted knockdown of Kv1.3 channels in T lymphocytes corrects the disease manifestations associated with systemic lupus erythematosus

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Science Advances  18 Nov 2020:
Vol. 6, no. 47, eabd1471
DOI: 10.1126/sciadv.abd1471

Article Information

vol. 6 no. 47

PubMed: 
Online ISSN: 
History: 
  • Received for publication June 3, 2020
  • Accepted for publication October 2, 2020
  • .

Author Information

  1. Marat Khodoun1,2,*,
  2. Ameet A. Chimote3,*,
  3. Farhan Z. Ilyas3,
  4. Heather J. Duncan3,
  5. Halima Moncrieffe4,5,
  6. K. Shashi Kant3 and
  7. Laura Conforti3,
  1. 1Division of Rheumatology, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.
  2. 2Division of Immunobiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.
  3. 3Division of Nephrology, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.
  4. 4Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.
  5. 5Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
  1. Corresponding author. Email: laura.conforti{at}uc.edu
  • * These authors contributed equally to this work.

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