Research ArticleHEALTH AND MEDICINE
A facile one-stage treatment of critical bone defects using a calcium sulfate/hydroxyapatite biomaterial providing spatiotemporal delivery of bone morphogenic protein–2 and zoledronic acid
- View ORCID ProfileDeepak Bushan Raina1,*,
- Lucas-Maximilian Matuszewski2,
- View ORCID ProfileCorina Vater2,
- View ORCID ProfileJulia Bolte2,
- View ORCID ProfileHanna Isaksson1,3,
- Lars Lidgren1,
- View ORCID ProfileMagnus Tägil1 and
- View ORCID ProfileStefan Zwingenberger2
- 1Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Orthopaedics, Lund 22185, Sweden.
- 2University Hospital Carl Gustav Carus at Technische Universität Dresden, University Center of Orthopedic, Trauma and Plastic Surgery, Dresden 01307, Germany.
- 3Lund University, Department of Biomedical Engineering, Lund 22100, Sweden.
- ↵*Corresponding author. Email: deepak.raina{at}med.lu.se
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Science Advances 27 Nov 2020:
Vol. 6, no. 48, eabc1779
DOI: 10.1126/sciadv.abc1779
Vol. 6, no. 48, eabc1779
DOI: 10.1126/sciadv.abc1779
Deepak Bushan Raina
1Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Orthopaedics, Lund 22185, Sweden.
Lucas-Maximilian Matuszewski
2University Hospital Carl Gustav Carus at Technische Universität Dresden, University Center of Orthopedic, Trauma and Plastic Surgery, Dresden 01307, Germany.
Corina Vater
2University Hospital Carl Gustav Carus at Technische Universität Dresden, University Center of Orthopedic, Trauma and Plastic Surgery, Dresden 01307, Germany.
Julia Bolte
2University Hospital Carl Gustav Carus at Technische Universität Dresden, University Center of Orthopedic, Trauma and Plastic Surgery, Dresden 01307, Germany.
Hanna Isaksson
1Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Orthopaedics, Lund 22185, Sweden.
3Lund University, Department of Biomedical Engineering, Lund 22100, Sweden.
Lars Lidgren
1Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Orthopaedics, Lund 22185, Sweden.
Magnus Tägil
1Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Orthopaedics, Lund 22185, Sweden.
Stefan Zwingenberger
2University Hospital Carl Gustav Carus at Technische Universität Dresden, University Center of Orthopedic, Trauma and Plastic Surgery, Dresden 01307, Germany.