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Noninvasive characterization of Alzheimer’s disease by circulating, cell-free messenger RNA next-generation sequencing

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Science Advances  09 Dec 2020:
Vol. 6, no. 50, eabb1654
DOI: 10.1126/sciadv.abb1654

Article Information

vol. 6 no. 50

PubMed: 
Online ISSN: 
History: 
  • Received for publication February 4, 2020
  • Accepted for publication October 21, 2020
  • .

Author Information

  1. Shusuke Toden1,*,,
  2. Jiali Zhuang1,*,
  3. Alexander D. Acosta1,
  4. Amy P. Karns1,
  5. Neeraj S. Salathia1,,
  6. James B. Brewer2,
  7. Donna M. Wilcock3,
  8. Jonathan Aballi1,
  9. Mike Nerenberg1,
  10. Stephen R. Quake4,5 and
  11. Arkaitz Ibarra1,
  1. 1Molecular Stethoscope Inc., 3210 Merryfield Row, San Diego, CA 92121, USA.
  2. 2Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  3. 3Department of Physiology, Sanders-Brown Center on Aging, 800 S. Limestone Street, Lexington, KY 40536, USA.
  4. 4Departments of Bioengineering and Applied Physics, Stanford University, Stanford, CA 94305, USA.
  5. 5Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.
  1. Corresponding author. Email: stoden{at}molecularstethoscope.com (S.T.); aibarra{at}molecularstethoscope.com (A.I.)
  • * These authors contributed equally to this work.

  • Present address: Bristol Myers Squibb, 9360 Towne Centre Drive, San Diego, CA 92121, USA.

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