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A mathematical model of ctDNA shedding predicts tumor detection size

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Science Advances  11 Dec 2020:
Vol. 6, no. 50, eabc4308
DOI: 10.1126/sciadv.abc4308

Article Information

vol. 6 no. 50

PubMed: 
Online ISSN: 
History: 
  • Received for publication April 24, 2020
  • Accepted for publication October 29, 2020
  • .

Author Information

  1. Stefano Avanzini1,
  2. David M. Kurtz2,
  3. Jacob J. Chabon3,4,
  4. Everett J. Moding4,5,
  5. Sharon Seiko Hori1,6,
  6. Sanjiv Sam Gambhir1,4,6,7,8,*,
  7. Ash A. Alizadeh2,3,4,
  8. Maximilian Diehn3,4,5 and
  9. Johannes G. Reiter1,4,7,9,
  1. 1Canary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Palo Alto, CA 94304, USA.
  2. 2Division of Oncology, Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  3. 3Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  4. 4Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
  5. 5Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  6. 6Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  7. 7Bio-X Program, Stanford University, Stanford, CA 94305, USA.
  8. 8Department of Bioengineering and Department of Materials Science and Engineering, Stanford University School of Medicine, Palo Alto, CA 94305, USA.
  9. 9Department of Biomedical Data Science, Biophysics Program, Stanford University, Stanford, CA 94305, USA.
  1. Corresponding author. Email: johannes.reiter{at}stanford.edu

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Article usage: December 2020 to July 2021

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Dec 202016963292380
Jan 2021811416639
Feb 202153585252
Mar 202155683247
Apr 202131611224
May 202190483229
Jun 202134417209
Jul 202144348178

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