Research ArticleSTRUCTURAL BIOLOGY

Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography

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Science Advances  09 Dec 2020:
Vol. 6, no. 50, eabc8262
DOI: 10.1126/sciadv.abc8262

Article Information

vol. 6 no. 50

PubMed: 
Online ISSN: 
History: 
  • Received for publication May 15, 2020
  • Accepted for publication October 21, 2020
  • .

Author Information

  1. Kate L. White1,2,*,
  2. Jitin Singla1,3,
  3. Valentina Loconte4,
  4. Jian-Hua Chen2,5,
  5. Axel Ekman5,
  6. Liping Sun4,
  7. Xianjun Zhang1,
  8. John Paul Francis6,
  9. Angdi Li4,
  10. Wen Lin7,
  11. Kaylee Tseng1,
  12. Gerry McDermott2,5,
  13. Frank Alber1,3,
  14. Andrej Sali8,*,
  15. Carolyn Larabell2,5,* and
  16. Raymond C. Stevens1,4,7,*
  1. 1Department of Biological Sciences, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA 90089, USA.
  2. 2Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  3. 3Institute for Quantitative and Computational Biosciences, Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  4. 4iHuman Institute, School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
  5. 5Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.
  6. 6Department of Computer Science, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA 90089, USA.
  7. 7Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA 90089, USA.
  8. 8California Institute for Quantitative Biosciences, Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA.
  1. *Corresponding author. Email: stevens{at}usc.edu (R.C.S.); calarabell{at}lbl.gov (C.L.); sali{at}salilab.org (A.S.); katewhit{at}usc.edu (K.L.W.)

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