Research ArticleCELL BIOLOGY

The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes

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Science Advances  16 Dec 2020:
Vol. 6, no. 51, eabc7209
DOI: 10.1126/sciadv.abc7209

Article Information

vol. 6 no. 51

PubMed: 
Online ISSN: 
History: 
  • Received for publication May 10, 2020
  • Accepted for publication October 27, 2020
  • .

Author Information

  1. Meng Lu1,2,
  2. Francesca W. van Tartwijk2,*,
  3. Julie Qiaojin Lin2,3,*,
  4. Wilco Nijenhuis4,
  5. Pierre Parutto5,,
  6. Marcus Fantham2,,
  7. Charles N. Christensen2,
  8. Edward Avezov3,
  9. Christine E. Holt6,
  10. Alan Tunnacliffe1,
  11. David Holcman5,7,
  12. Lukas Kapitein4,
  13. Gabriele S. Kaminski Schierle1,2 and
  14. Clemens F. Kaminski1,2,3,§
  1. 1Cambridge Infinitus Research Centre, Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
  2. 2Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
  3. 3UK Dementia Research Institute at the University of Cambridge and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.
  4. 4Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands.
  5. 5Group of Computational Biology and Applied Mathematics, Institut de Biologie de l’École Normale Supérieure-PSL, 46 rue d’Ulm, 75005 Paris, France.
  6. 6Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK.
  7. 7Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge CB3 0WA, UK.
  1. §Corresponding author. Email: cfk23{at}cam.ac.uk
  • * These authors contributed equally to this work.

  • Present address: UK Dementia Research Institute at the University of Cambridge and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.

  • Present address: Oxford Nanoimaging, Linacre House, Banbury Rd, Oxford OX2 8TA, UK.

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