Research ArticleCANCER
Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms
- View ORCID ProfileMark Borris D. Aldonza1,2,3,
- View ORCID ProfileJayoung Ku1,3,
- View ORCID ProfileJi-Young Hong4,
- Donghwa Kim4,
- Seung Jung Yu1,
- Min-Seok Lee1,
- Monica Celine Prayogo1,
- Stephanie Tan1,
- View ORCID ProfileDayeon Kim5,
- View ORCID ProfileJinju Han5,6,
- View ORCID ProfileSang Kook Lee4,
- View ORCID ProfileSung Gap Im1,
- Han Suk Ryu7 and
- View ORCID ProfileYoosik Kim1,3,*
- 1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
- 2Department of Biological Sciences, KAIST, Daejeon 34141, Korea.
- 3KI for Health Science and Technology (KIHST), KAIST, Daejeon 34141, Korea.
- 4College of Pharmacy, Seoul National University, Seoul 08826, Korea.
- 5Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon 34141, Korea.
- 6Graduate School of Medical Science and Engineering (GSMSE), KAIST, Daejeon 34141, Korea.
- 7Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 03080, Korea.
- ↵*Corresponding author. Email: ysyoosik{at}kaist.ac.kr
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Science Advances 07 Feb 2020:
Vol. 6, no. 6, eaav7416
DOI: 10.1126/sciadv.aav7416
Vol. 6, no. 6, eaav7416
DOI: 10.1126/sciadv.aav7416
Mark Borris D. Aldonza
1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
2Department of Biological Sciences, KAIST, Daejeon 34141, Korea.
3KI for Health Science and Technology (KIHST), KAIST, Daejeon 34141, Korea.
Jayoung Ku
1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
3KI for Health Science and Technology (KIHST), KAIST, Daejeon 34141, Korea.
Ji-Young Hong
4College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Donghwa Kim
4College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Seung Jung Yu
1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Min-Seok Lee
1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Monica Celine Prayogo
1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Stephanie Tan
1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Dayeon Kim
5Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon 34141, Korea.
Jinju Han
5Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon 34141, Korea.
6Graduate School of Medical Science and Engineering (GSMSE), KAIST, Daejeon 34141, Korea.
Sang Kook Lee
4College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Sung Gap Im
1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Han Suk Ryu
7Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 03080, Korea.
Yoosik Kim
1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
3KI for Health Science and Technology (KIHST), KAIST, Daejeon 34141, Korea.
