Research ArticleMOLECULAR BIOLOGY

Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions

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Science Advances  19 Feb 2020:
Vol. 6, no. 8, eaax5783
DOI: 10.1126/sciadv.aax5783

Article Information

vol. 6 no. 8

Online ISSN: 
History: 
  • Received for publication April 4, 2019
  • Accepted for publication December 11, 2019
  • .

Author Information

  1. M. A. Gonzalez-Lozano1,
  2. F. Koopmans1,
  3. P. F. Sullivan2,3,
  4. J. Protze4,
  5. G. Krause4,
  6. M. Verhage5,
  7. K. W. Li1,*,
  8. F. Liu6,7,*, and
  9. A. B. Smit1,*,
  1. 1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  2. 2Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
  3. 3Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
  4. 4Department of Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.
  5. 5Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  6. 6Department of Chemical Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.
  7. 7Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.
  1. *Corresponding author. Email: k.w.li{at}vu.nl (K.W.L.); fliu{at}fmp-berlin.de (F.L.); guus.smit{at}vu.nl (A.B.S.)
  • These authors contributed equally to this work.

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