Research ArticleBIOPHYSICS
Grid diagrams as tools to investigate knot spaces and topoisomerase-mediated simplification of DNA topology
- View ORCID ProfileAgnese Barbensi1,
- Daniele Celoria1,
- Heather A. Harrington1,*,
- View ORCID ProfileAndrzej Stasiak2,3,* and
- View ORCID ProfileDorothy Buck4,5,*
- 1Mathematical Institute, University of Oxford, Oxford, UK.
- 2Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
- 3SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.
- 4Department of Mathematical Sciences, University of Bath, Bath, UK.
- 5Department of Mathematics/Biology, Trinity College of Arts and Sciences, Duke University, Durham, NC, USA.
- ↵*Corresponding author. Email: harrington{at}maths.ox.ac.uk (H.A.H.); d.buck{at}bath.ac.uk (D.B.); andrzej.stasiak{at}unil.ch (A.S.)
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Science Advances 26 Feb 2020:
Vol. 6, no. 9, eaay1458
DOI: 10.1126/sciadv.aay1458
Vol. 6, no. 9, eaay1458
DOI: 10.1126/sciadv.aay1458
Agnese Barbensi
1Mathematical Institute, University of Oxford, Oxford, UK.
Daniele Celoria
1Mathematical Institute, University of Oxford, Oxford, UK.
Heather A. Harrington
1Mathematical Institute, University of Oxford, Oxford, UK.
Andrzej Stasiak
2Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
3SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Dorothy Buck
4Department of Mathematical Sciences, University of Bath, Bath, UK.
5Department of Mathematics/Biology, Trinity College of Arts and Sciences, Duke University, Durham, NC, USA.