Research ArticleCORONAVIRUS
Damaged lung gas exchange function of discharged COVID-19 patients detected by hyperpolarized 129Xe MRI
- View ORCID ProfileHaidong Li1,*,
- Xiuchao Zhao1,*,
- View ORCID ProfileYujin Wang2,*,
- View ORCID ProfileXin Lou3,*,
- Shizhen Chen1,
- View ORCID ProfileHe Deng1,
- View ORCID ProfileLei Shi1,
- Junshuai Xie1,
- View ORCID ProfileDazhong Tang2,
- Jianping Zhao2,
- Louis-S. Bouchard4,
- View ORCID ProfileLiming Xia2,† and
- View ORCID ProfileXin Zhou1,†
- 1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.
- 2Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P. R. China.
- 3Department of Radiology, Chinese PLA General Hospital, Beijing 100853, P. R. China.
- 4Jonsson Comprehensive Cancer Center, The Molecular Biology Institute, California NanoSystems Institute, Departments of Chemistry and Biochemistry and of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
- ↵†Corresponding author. Email: xinzhou{at}wipm.ac.cn (X.Z.); lmxia{at}tjh.tjmu.edu.cn (L.X.)
↵* These authors contributed equally to this work.
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Science Advances 01 Jan 2021:
Vol. 7, no. 1, eabc8180
DOI: 10.1126/sciadv.abc8180
Vol. 7, no. 1, eabc8180
DOI: 10.1126/sciadv.abc8180
Haidong Li
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.
Xiuchao Zhao
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.
Yujin Wang
2Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P. R. China.
Xin Lou
3Department of Radiology, Chinese PLA General Hospital, Beijing 100853, P. R. China.
Shizhen Chen
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.
He Deng
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.
Lei Shi
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.
Junshuai Xie
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.
Dazhong Tang
2Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P. R. China.
Jianping Zhao
2Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P. R. China.
Louis-S. Bouchard
4Jonsson Comprehensive Cancer Center, The Molecular Biology Institute, California NanoSystems Institute, Departments of Chemistry and Biochemistry and of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Liming Xia
2Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P. R. China.
Xin Zhou
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.
