Research ArticleCORONAVIRUS
Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening
- View ORCID ProfileDaniel B. Larremore1,2,*,
- Bryan Wilder3,
- View ORCID ProfileEvan Lester4,5,
- Soraya Shehata5,6,
- James M. Burke4,
- View ORCID ProfileJames A. Hay7,8,
- View ORCID ProfileMilind Tambe3,
- View ORCID ProfileMichael J. Mina7,8,9,*,† and
- View ORCID ProfileRoy Parker2,4,6,10,*,†
- 1Department of Computer Science, University of Colorado Boulder.
- 2BioFrontiers Institute, University of Colorado Boulder.
- 3Center for Research on Computation and Society, Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University.
- 4Department of Biochemistry, University of Colorado Boulder.
- 5Medical Scientist Training Program, University of Colorado Anschutz Medical Campus.
- 6Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder.
- 7Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health.
- 8Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health.
- 9Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School.
- 10Howard Hughes Medical Institute.
- ↵*Corresponding author. Email: daniel.larremore{at}colorado.edu (D.B.L.); mmina{at}hsph.harvard.edu (M.J.M.); roy.parker{at}colorado.edu (R.P.)
↵† These authors contributed equally to this work.
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Science Advances 01 Jan 2021:
Vol. 7, no. 1, eabd5393
DOI: 10.1126/sciadv.abd5393
Vol. 7, no. 1, eabd5393
DOI: 10.1126/sciadv.abd5393
Daniel B. Larremore
1Department of Computer Science, University of Colorado Boulder.
2BioFrontiers Institute, University of Colorado Boulder.
Bryan Wilder
3Center for Research on Computation and Society, Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University.
Evan Lester
4Department of Biochemistry, University of Colorado Boulder.
5Medical Scientist Training Program, University of Colorado Anschutz Medical Campus.
Soraya Shehata
5Medical Scientist Training Program, University of Colorado Anschutz Medical Campus.
6Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder.
James M. Burke
4Department of Biochemistry, University of Colorado Boulder.
James A. Hay
7Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health.
8Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health.
Milind Tambe
3Center for Research on Computation and Society, Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University.
Michael J. Mina
7Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health.
8Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health.
9Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School.
Roy Parker
2BioFrontiers Institute, University of Colorado Boulder.
4Department of Biochemistry, University of Colorado Boulder.
6Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder.
10Howard Hughes Medical Institute.