Research ArticleCELL BIOLOGY

Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction

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Science Advances  12 Mar 2021:
Vol. 7, no. 11, eabe4501
DOI: 10.1126/sciadv.abe4501

Article Information

vol. 7 no. 11

PubMed: 
Online ISSN: 
History: 
  • Received for publication August 21, 2020
  • Accepted for publication January 27, 2021
  • .

Author Information

  1. Jason S. Silver1,2,3,4,
  2. K. Arda Günay1,2,
  3. Alicia A. Cutler3,
  4. Thomas O. Vogler3,4,
  5. Tobin E. Brown1,2,
  6. Bradley T. Pawlikowski3,
  7. Olivia J. Bednarski1,2,
  8. Kendra L. Bannister1,2,
  9. Cameron J. Rogowski1,2,
  10. Austin G. Mckay1,2,
  11. Frank W. DelRio5,
  12. Bradley B. Olwin2,3,* and
  13. Kristi S. Anseth1,2,*
  1. 1Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO, USA.
  2. 2BioFrontiers Institute, University of Colorado, Boulder, CO, USA.
  3. 3Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, USA.
  4. 4Medical Scientist Training Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  5. 5Applied Chemicals and Materials Division, Material Measurement Laboratory, National Institute of Standards and Technology, Boulder, CO, USA.
  1. *Corresponding author. Email: kristi.anseth{at}colorado.edu (K.S.A.); olwin{at}colorado.edu (B.B.O.)

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