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Nanotransfection-based vasculogenic cell reprogramming drives functional recovery in a mouse model of ischemic stroke

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Science Advances  19 Mar 2021:
Vol. 7, no. 12, eabd4735
DOI: 10.1126/sciadv.abd4735

Article Information

vol. 7 no. 12

PubMed: 
Online ISSN: 
History: 
  • Received for publication June 23, 2020
  • Accepted for publication January 22, 2021
  • .

Author Information

  1. Luke R. Lemmerman1,
  2. Maria H. H. Balch2,
  3. Jordan T. Moore1,
  4. Diego Alzate-Correa1,
  5. Maria A. Rincon-Benavides1,
  6. Ana Salazar-Puerta1,
  7. Surya Gnyawali2,
  8. Hallie N. Harris2,
  9. William Lawrence1,3,
  10. Lilibeth Ortega-Pineda1,
  11. Lauren Wilch4,
  12. Ian B. Risser1,
  13. Aidan J. Maxwell5,
  14. Silvia Duarte-Sanmiguel1,6,
  15. Daniel Dodd1,3,
  16. Gina P. Guio-Vega1,7,
  17. Dana M. McTigue8,
  18. W. David Arnold9,
  19. Shahid M. Nimjee2,
  20. Chandan K. Sen10,
  21. Savita Khanna10,
  22. Cameron Rink2,
  23. Natalia Higuita-Castro1,11,* and
  24. Daniel Gallego-Perez1,11,*
  1. 1Department of Biomedical Engineering, The Ohio State University, Columbus, OH 43210, USA.
  2. 2Department of Neurosurgery, The Ohio State University, Columbus, OH 43210, USA.
  3. 3Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH 43210, USA.
  4. 4Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.
  5. 5Department of Biology, The Ohio State University, Columbus, OH 43210, USA.
  6. 6OSU Nutrition, The Ohio State University, Columbus, OH 43210, USA.
  7. 7Department of Medicine, National University of Colombia, Bogotá, Colombia
  8. 8Department of Neuroscience, The Ohio State University, Columbus, OH 43210, USA.
  9. 9Department of Neurology, The Ohio State University, Columbus, OH 43210, USA.
  10. 10Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
  11. 11Department of Surgery, The Ohio State University, Columbus, OH 43210, USA.
  1. *Corresponding author. Email: gallegoperez.1{at}osu.edu (D.G.-P.); higuitacastro.1{at}osu.edu (N.H.-C.)

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