Research ArticleCELL BIOLOGY

AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy

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Science Advances  07 Apr 2021:
Vol. 7, no. 15, eabg4544
DOI: 10.1126/sciadv.abg4544

Article Information

vol. 7 no. 15

PubMed: 
Online ISSN: 
History: 
  • Received for publication January 6, 2021
  • Accepted for publication February 18, 2021
  • .

Author Information

  1. Chien-Min Hung1,,
  2. Portia S. Lombardo1,,
  3. Nazma Malik1,
  4. Sonja N. Brun1,
  5. Kristina Hellberg1,
  6. Jeanine L. Van Nostrand1,
  7. Daniel Garcia1,
  8. Joshua Baumgart1,
  9. Ken Diffenderfer2,
  10. John M. Asara3 and
  11. Reuben J. Shaw1,*
  1. 1Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  2. 2Stem Cell Core Facility, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  3. 3Mass Spectrometry Core, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  1. *Corresponding author. Email: shaw{at}salk.edu
  • These authors contributed equally to this work.

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