Research ArticleBIOPHYSICS

A highly conserved 310 helix within the kinesin motor domain is critical for kinesin function and human health

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Science Advances  30 Apr 2021:
Vol. 7, no. 18, eabf1002
DOI: 10.1126/sciadv.abf1002

Article Information

vol. 7 no. 18

PubMed: 
Online ISSN: 
History: 
  • Received for publication October 3, 2020
  • Accepted for publication March 11, 2021
  • .

Author Information

  1. Aileen J. Lam1,
  2. Lu Rao2,
  3. Yuzu Anazawa3,4,
  4. Kyoko Okada1,
  5. Kyoko Chiba1,4,
  6. Mariah Dacy1,
  7. Shinsuke Niwa4,
  8. Arne Gennerich2,*,
  9. Dan W. Nowakowski5,* and
  10. Richard J. McKenney1,*
  1. 1Department of Molecular and Cellular Biology, University of California, Davis. Davis, CA 95616, USA.
  2. 2Department of Anatomy and Structural Biology and Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  3. 3Department of Biology, Faculty of Science, Tohoku University, Sendai, 980-8578 Miyagi, Japan.
  4. 4Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, 980-0845 Miyagi, Japan.
  5. 5N Molecular Systems Inc., Palo Alto, CA 94303, USA.
  1. *Corresponding author. Email: arne.gennerich{at}einsteinmed.org (A.G.); publications{at}nmolecularsystems.com (D.W.N.); rjmckenney{at}ucdavis.edu (R.J.M.)

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