Contents
January 2021
Vol 7, Issue 2
Vol 7, Issue 2
Contents
Research Articles
- Peer review and gender bias: A study on 145 scholarly journals
No evidence that women are penalized in peer review and editorial processes, finds study on 145 journals in multiple disciplines.
- Critical role of synovial tissue–resident macrophage niche in joint homeostasis and suppression of chronic inflammation
Using a novel model of rheumatoid arthritis, we identified a critical role for reduced tissue-resident macrophages.
- Controlled emission time statistics of a dynamic single-electron transistor
Accurate control of the emission time statistics is demonstrated for a dynamic single-electron transistor.
- The structure of enteric human adenovirus 41—A leading cause of diarrhea in children
A cryo-EM structure reveals unique traits of a human adenovirus that has acquired gastrointestinal tropism.
- Observation of chiral edge states in gapped nanomechanical graphene
We experimentally realized quantum valley Hall chiral edge states in nanomechanical graphene by tuning the boundary potential.
- Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin
Gene therapy for tuberous sclerosis type 2 proved beneficial in a mouse model of the disease, extending life span.
- A circadian clock in a nonphotosynthetic prokaryote
Bacillus subtilis has a circadian clock, extending the field of chronobiology to nonphotosynthetic bacteria.
- Ultrabright Au@Cu14 nanoclusters: 71.3% phosphorescence quantum yield in non-degassed solution at room temperature
Single-gold-atom doping into a copper nanocluster lights up phosphorescence via triplet-state engineering.
- Tb3+-doped fluorescent glass for biology
Tb3+-doped glass emits GFP-like fluorescence and is versatile for various biological research purposes.
- Heating events in the nascent solar system recorded by rare earth element isotopic fractionation in refractory inclusions
The compositions of the first solar system solids were shaped by nonequilibrium condensation and evaporation.
- Perfusion, cryopreservation, and nanowarming of whole hearts using colloidally stable magnetic cryopreservation agent solutions
Colloidally stable nanoparticles and magnetic cryopreservation agents can be used for cryopreservation and nanowarming of hearts.
- A thin, deformable, high-performance supercapacitor implant that can be biodegraded and bioabsorbed within an animal body
A soft, biocompatible, high-performance supercapacitor implant is degradable and can be absorbed within an animal body.
- Dynamic thermal trapping enables cross-species smart nanoparticle swarms
Smart nanoparticle swarm allows dynamic multimaterials integration to access distinctive functions.
- A smartphone-read ultrasensitive and quantitative saliva test for COVID-19
An isolation-free smartphone-based saliva assay can diagnose COVID-19 cases and quantify viral load within 15 min.
- Adiponectin receptor 1 variants contribute to hypertrophic cardiomyopathy that can be reversed by rapamycin
Gene variants in adiponectin receptor 1 cause pathological enlarged hearts.
- The nuclear piston activates mechanosensitive ion channels to generate cell migration paths in confining microenvironments
Cells utilize a nuclear piston to mechanically generate migration paths in confining matrices.
- Isomer-specific kinetics of the C+ + H2O reaction at the temperature of interstellar clouds
An important interstellar hydrocarbon chemical reaction has been measured in a laboratory.
- Feeding diverse prey as an excellent strategy of mixotrophic dinoflagellates for global dominance
Mixotrophic dinoflagellate species with low or moderate growth rates but diverse prey cause red tides globally.
- Single-crystalline epitaxial TiO film: A metal and superconductor, similar to Ti metal
Epitaxial TiO(001) film grown by MBE is found to be the only metal and superconductor among 3d transition-metal monoxides.
- 3D printing of highly stretchable hydrogel with diverse UV curable polymers
This article proposes an approach of 3D printing structures consisting of stretchable hydrogels bonded with UV curable polymers.
- Dynamic band structure measurement in the synthetic space
Experimental measurement of dynamic band structure exhibits the evolution of the wave vector in a synthetic lattice.
- Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies
Cryo-EM studies of the yeast HDAC complex with and without nucleosome reveal mechanistic insight into chromatin modification.
- Human population dynamics and Yersinia pestis in ancient northeast Asia
Ancient genomes reveal a complex demographic picture since the post-LGM in northeast Asia and report the presence of Y. pestis.
- Tunable intraband optical conductivity and polarization-dependent epsilon-near-zero behavior in black phosphorus
Tunable BP heterostructures enable observation of the intraband optical conductivity and active control of optical dispersion.
- Polarization-sensitive stimulated Raman scattering imaging resolves amphotericin B orientation in Candida membrane
Label-free stimulated Raman scattering microscopy resolves amphotericin B orientation in fungal cell membrane.
- Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets
Three major molecular subtypes of Alzheimer’s disease are identified, cross-validated, and characterized across 1543 individuals.
- Structure of cyanobacterial phycobilisome core revealed by structural modeling and chemical cross-linking
Cyanobacterial light-harvesting complex features efficient energy capture, transmission, and regulation to reaction centers.
- Crystal orientation dictated epitaxy of ultrawide-bandgap 5.4- to 8.6-eV α-(AlGa)2O3 on m-plane sapphire
Crystalline oxides spanning very broad 5.4- to 8.6-eV bandgaps are successfully grown on sapphire by MBE.
- Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA–induced dyskinesia
l-DOPA–induced dyskinesia is caused by elevated l-DOPA levels and dysregulated l-DOPA metabolism throughout the brain.
- Defects and plasticity in ultrastrong supercrystalline nanocomposites
Supercrystalline nanocomposites deform plastically like atomic crystals, even after a boost in strength, and feature compaction.
- Genetic switch in UV response of mimicry-related pale-yellow colors in Batesian mimic butterfly, Papilio polytes
UV response switch of a wing color in Papilio polytes butterflies is important for dimorphic female-limited Batesian mimicry.
- Rotational Doppler cooling and heating
Rotational Doppler cooling and heating are generalized from their translational counterparts, revealing dissimilar physics.
- Partisan pandemic: How partisanship and public health concerns affect individuals’ social mobility during COVID-19
Partisanship affects efforts to limit social mobility.
- Amorphization mechanism of SrIrO3 electrocatalyst: How oxygen redox initiates ionic diffusion and structural reorganization
The transformation from crystalline SrIrO3 to active amorphous iridium oxide electrocatalyst occurs via the lattice oxygen redox.
- ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism
ITIH4 forms complexes with proteases upon cleavage that inhibit proteolysis by a novel inhibitory mechanism.
- Gene expression signatures of target tissues in type 1 diabetes, lupus erythematosus, multiple sclerosis, and rheumatoid arthritis
Target tissues of four autoimmune diseases show similar gene expression signatures emphasizing a dialog immune cell-target tissue.
- Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway
CRISPR-based bioengineering of the transferrin receptor reveals a new role for Rab7 in the biosynthetic secretory pathway.
- Acoustohydrodynamic tweezers via spatial arrangement of streaming vortices
Decomposition and control of acoustic streaming enable contact-free manipulation of bioanalytes and digitalized liquid handling.
- Antiferromagnetic switching driven by the collective dynamics of a coexisting spin glass
Collective motion of correlated spins is demonstrated as a way to control antiferromagnetic memory in quantum technologies.
- Carbon isotope evidence for the global physiology of Proterozoic cyanobacteria
Carboxysomes evolved due to rising O2, not falling CO2, enabling planktic cyanobacteria to flourish during earth’s middle age.
- Acoustic spin Hall effect in strong spin-orbit metals
We have found the acoustic spin Hall effect that facilitates lattice motion-induced spin current in strong spin-orbit metals.
- TRIM26 is a critical host factor for HCV replication and contributes to host tropism
A genome-wide screening revealed that TRIM26 is a host factor for HCV replication and a new determinant for host tropism.
- Thermal stress reduces pocilloporid coral resilience to ocean acidification by impairing control over calcifying fluid chemistry
Thermal stress reduces pocilloporid coral resilience to ocean acidification by impairing control over calcifying fluid chemistry.
Reviews
- Controlling electrochemical growth of metallic zinc electrodes: Toward affordable rechargeable energy storage systems
Zinc anodes are a powerful platform for understanding metal deposition and for low-cost electrical energy storage.
- The gill-oxygen limitation theory (GOLT) and its critics
The gill-oxygen limitation theory (GOLT) explains many previously unexplained aspects of the life history of fish.
About The Cover
ONLINE COVER Hydrogel-polymer hybrids are used for a wide variety of applications, including biomedical devices and flexible electronics. However, these useful materials have their limits—current technologies are constrained to laminates, which consist of fixed layers of hydrogel and silicone rubbers. To explore a more versatile way to fabricate complex hydrogel-polymer hybrids, Ge et al. developed a multimaterial 3D printing approach, which involved a self-built 3D printer based on digital light processing (DLP). The researchers applied this approach to construct hybrid 3D structures consisting of highly stretchable acrylamide-PEGDA (AP) hydrogels with high water content, which were covalently bonded with diverse UV curable polymers. Ge et al. demonstrated that the technique could be used for applications including a 3D printed meniscus with spatially variable stiffness and a 4D printed cardiovascular stent capable of performing drug delivery. Ge et al. suggest this approach introduces a new way to build multifunctional soft devices and machines, with the potential to impact biomedicine, soft robotics, flexible electronics, and other fields. [CREDIT: QI GE]
