Research ArticleVIROLOGY

TRIM26 is a critical host factor for HCV replication and contributes to host tropism

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Science Advances  08 Jan 2021:
Vol. 7, no. 2, eabd9732
DOI: 10.1126/sciadv.abd9732

Article Information

vol. 7 no. 2

Online ISSN: 
  • Received for publication July 24, 2020
  • Accepted for publication November 13, 2020
  • .

Author Information

  1. Yisha Liang1,2,3,*,
  2. Guigen Zhang4,5,*,,
  3. Qiheng Li4,*,
  4. Lin Han1,2,3,
  5. Xiaoyou Hu1,3,
  6. Yu Guo4,
  7. Wanyin Tao1,,
  8. Xiaomin Zhao6,
  9. Mingzhe Guo1,2,3,
  10. Tianyu Gan1,3,
  11. Yimin Tong1,
  12. Yongfen Xu1,
  13. Zhuo Zhou4,
  14. Qiang Ding6,
  15. Wensheng Wei4, and
  16. Jin Zhong1,2,3,
  1. 1Unit of Viral Hepatitis, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China.
  2. 2School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
  3. 3University of Chinese Academy of Sciences, Beijing 100049, China.
  4. 4Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing 100871, China.
  5. 5Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong 510000, China.
  6. 6Center for Infectious Diseases Research, School of Medicine, Tsinghua University, Beijing 100084, China.
  1. Corresponding author. Email: jzhong{at} (J.Z.); wswei{at} (W.W.); zhanggg5{at} (G.Z.)
  • * Co-first authors.

  • Present address: Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Science and Medicine, University of Science and Technology of China, Hefei 230000, China.


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