May 2021
Vol 7, Issue 20

About The Cover

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ONLINE COVER Signals related to cerebral blood flow, which is essential for brain function, can provide important insights into brain activity. However, scientists currently must use high-end, expensive medical instruments to measure cerebral brain flow in adult humans and lack the ability to continuously monitor brain function during everyday activities. To better monitor optical blood flow index measurements (a surrogate for cerebral blood flow) in the human brain, Zhou et al. developed a new technology called functional interferometric Diffusing Wave Spectroscopy (fiDWS). This technology uses an inexpensive detector to monitor fluctuations in near-infrared light near the scalp, which encode the brain blood flow index. This approach measures brain blood flow index faster and deeper than existing functional optical approaches while providing continuous wave absorption signals. The authors note that this is the first system in 20 years of prior research that succeeds in penetrating human brain tissue to a depth of 1 to 2 centimeters to measure functional optical blood flow index, resulting in an exceptionally sensitive method for assessing human brain function. Zhou and colleagues suggest that fiDWS will expand access to CBF by providing high throughput measurements at low cost. [CREDIT: LETPUB]