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Research ArticleIMMUNOLOGY
Substrate-specific recognition of IKKs mediated by USP16 facilitates autoimmune inflammation
- View ORCID ProfileJian-shuai Yu1,*,
- View ORCID ProfileTao Huang1,*,
- View ORCID ProfileYu Zhang2,*,
- Xin-tao Mao1,
- Ling-jie Huang2,
- Yi-ning Li1,
- Ting-ting Wu2,
- Jiang-yan Zhong1,
- Qian Cao2,
- View ORCID ProfileYi-yuan Li3,*,† and
- View ORCID ProfileJin Jin1,†,‡
- 1MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
- 2Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China.
- 3Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing 210096, China.
- ↵†Corresponding author. Email: jjin4{at}zju.edu.cn (J.J.); 103200067{at}seu.edu.cn (Y.-y.L.)
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Science Advances 13 Jan 2021:
Vol. 7, no. 3, eabc4009
DOI: 10.1126/sciadv.abc4009
Vol. 7, no. 3, eabc4009
DOI: 10.1126/sciadv.abc4009
Jian-shuai Yu
1MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Tao Huang
1MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Yu Zhang
2Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China.
Xin-tao Mao
1MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Ling-jie Huang
2Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China.
Yi-ning Li
1MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Ting-ting Wu
2Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China.
Jiang-yan Zhong
1MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Qian Cao
2Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China.
Yi-yuan Li
3Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing 210096, China.
Jin Jin
1MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
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