Research ArticleHEALTH AND MEDICINE

A microneedle platform for buccal macromolecule delivery

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Science Advances  22 Jan 2021:
Vol. 7, no. 4, eabe2620
DOI: 10.1126/sciadv.abe2620

Article Information

vol. 7 no. 4

PubMed: 
Online ISSN: 
History: 
  • Received for publication August 10, 2020
  • Accepted for publication December 4, 2020
  • .

Author Information

  1. Ester Caffarel-Salvador1,2,
  2. Soyoung Kim2,
  3. Vance Soares2,
  4. Ryan Yu Tian2,
  5. Sarah R. Stern2,
  6. Daniel Minahan2,
  7. Raissa Yona2,
  8. Xiaoya Lu2,
  9. Fauziah R. Zakaria2,*,
  10. Joy Collins2,3,
  11. Jacob Wainer2,,
  12. Jessica Wong2,
  13. Rebecca McManus2,
  14. Siddartha Tamang2,
  15. Shane McDonnell2,
  16. Keiko Ishida2,
  17. Alison Hayward2,3,4,
  18. Xiewen Liu2,5,
  19. František Hubálek6,
  20. Johannes Fels6,
  21. Andreas Vegge6,
  22. Morten Revsgaard Frederiksen6,
  23. Ulrik Rahbek6,
  24. Tadayuki Yoshitake7,
  25. James Fujimoto7,
  26. Niclas Roxhed2,8,
  27. Robert Langer1,2,9, and
  28. Giovanni Traverso2,3,9,
  1. 1Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  2. 2Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  3. 3Division of Gastroenterology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  4. 4Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  5. 5Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH, UK.
  6. 6Global Research Technologies, Global Drug Discovery, and Device R&D, Novo Nordisk A/S, Måløv, Denmark.
  7. 7Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  8. 8School of Electrical Engineering and Computer Science, Department of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden.
  9. 9Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  1. Corresponding author. Email: rlanger{at}mit.edu (R.L.); cgt20{at}mit.edu (G.T.)
  • * Present address: Fischell Department of Bioengineering, University of Maryland at College Park, MD 20742, USA.

  • Present address: Fractyl Laboratories Inc., 17 Hartwell Ave., Lexington, MA 02421, USA.

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